Specificity
This antibody reacts with an extracellular epitope of CD33, a 67 kDa type I transmembrane glycoprotein of the immunoglobulin superfamily, expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells, and mast cells. It is absent on platelets, lymphocytes, erythrocytes, and hematopoietic stem cells.