Anti-CD3 epsilon Antibody [RIV9] - BSA and Azide free (A253684)

Anti-CD3 epsilon Antibody [RIV9] - BSA and Azide free

Mouse monoclonal [RIV9] antibody to CD3 epsilon.

This antibody recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb is particularly useful for induction of T cell activation in vitro and in vivo due to its unusual IgG3 isotype.

Functional Studies, Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Mouse, Rat

Human peripheral lymphocytes.

Mouse

Monoclonal

RIV9

IgG3

Protein A chromatography.

1 mg/ml

20 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Store at 4°C.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD3 epsilon Antibody [RIV9] (A250504).

CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E