Anti-CD3 epsilon Antibody (A250509)

Anti-CD3 epsilon Antibody

Rabbit polyclonal antibody to CD3 epsilon.

This antibody recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

WB: 1-2 µg/ml

Human

This antibody is predicted to cross react with Ape, Orangutan, Gibbon, Chimpanzee, Monkey, Elephant, Horse, Bovine, Sheep, Porcine, Canine, Feline, Rabbit, Rat, Mouse, Guinea Pig, Hamster, Opossum, Frog, and Chicken.

Synthetic peptide corresponding to amino acids 156-168 of human CD3e.

ERPPPVPNPDYEP

Rabbit

Polyclonal

Protein A chromatography.

200 µg/ml

20 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD3 epsilon Antibody - BSA and Azide free (A253689).

CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E