Anti-CD3 Antibody [OKT3] (FITC) (A122122)

Anti-CD3 Antibody [OKT3] (FITC)

Mouse monoclonal [OKT3] antibody to CD3 (FITC).

This antibody recognizes an extracellular epitope on CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart, and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.

Flow Cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Human

Human PBMCs.

Mouse

Monoclonal

IgG2a

This antibody is conjugated with Fluorescein Isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!

CD3d, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain, T3D

This product is for research use only. It is not intended for diagnostic or therapeutic use.