Recombinant Anti-CD27 Antibody [rLPFS2/1611] (A250620)

Anti-CD27 Antibody [rLPFS2/1611]

Recombinant mouse monoclonal [rLPFS2/1611] antibody to CD27.

This antibody recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Flow Cytometry, IHC-P

Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml

Human

Recombinant fragment of human CD22 protein. The exact sequence is proprietary.

Mouse

Monoclonal

rLPFS2/1611

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

120 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD27 Antibody [rLPFS2/1611] - BSA and Azide free (A253800).

CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7