Recombinant Anti-CD27 Antibody [LPFS2/8574R] (A314638)

Anti-CD27 Antibody [LPFS2/8574R]

Recombinant rabbit monoclonal [LPFS2/8574R] antibody to CD27.

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Human peripheral blood lymphocytes. Human tonsil and lymph node.

IHC: 1-2 µg/ml

Human

Recombinant human full-length CD22 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

LPFS2/8574R

IgG

Protein A/G chromatography.

200 µg/ml

120 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7