Anti-CD18 Antibody [MEM-148] - Low endotoxin, Azide free (A85611)

Anti-CD18 Antibody [MEM-148] - Low endotoxin, Azide free

Mouse monoclonal [MEM-148] antibody to CD18.

The antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.

Flow Cytometry, IP, WB, Functional Studies

FUNC: This antibody induces homotypic cell aggregation and high-affinity LFA-1 conformation in resting leukocytes, Flow Cytometry: 1-5 µg/ml. The antibody MEM-148 is an excellent marker of activated myeloid cells, WB: Non-reducing conditions.

Human

This antibody does not cross react with Pig.

Peripheral blood mononuclear cells.

Mouse

Monoclonal

MEM-148

IgG1

Protein A chromatography.

1 mg/ml

90-95 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, Integrin beta-2, ITGB2, MFI7