Anti-Cd13 Antibody [CC81] (A280066)

Anti-Cd13 Antibody [CC81]

Mouse monoclonal [CC81] antibody to Cd13.

This antibody recognises bovine CD13, a 150 kDa type II membrane protein shown to be a metallopeptidase in humans. In cattle the antigen recognised by clone CC81 is primarily expressed on enterocytes and cells with a dendritic morphology in the small intestine. Clone CC81 also defines a subpopulation of dendritic cells in afferent lymph that are CC81 Ag +ve and SIRPalpha -ve, which show differences in their capacities to stimulate T cells and cytokine synthesis compared to the CC81 Ag –ve SIRPalpha +ve dendritic cells.

Flow Cytometry, IHC-Fr

Flow Cytometry: 1:100 - 1:1,000, IHC-Fr: 1:25 - 1:50, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Bovine

Cells from cattle intestine.

Mouse

Monoclonal

CC81

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti bovine CD13, clone CC81, recognises bovine CD13, a 150 kDa type II membrane protein shown to be a metallopeptidase in humans. In cattle the antigen recognised by clone CC81 is primarily expressed on enterocytes and cells with a dendritic morphology in the small intestine. Clone CC81 also defines a subpopulation of dendritic cells in afferent lymph that are CC81 Ag +ve and SIRPalpha -ve, which show differences in their capacities to stimulate T cells and cytokine synthesis compared to the CC81 Ag –ve SIRPalpha +ve dendritic cells.

Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, ANPEP, AP-M, AP-N, APN, CD103, gp150, hAPN, HML-1 antigen, Integrin alpha-E, Integrin alpha-IEL, ITGAE, Microsomal aminopeptidase, Mucosal lymphocyte 1 antigen, Myeloid plasma membrane glycoprotein CD13, PEPN