Anti-CD11c Antibody [BAQ153A] (A279780)

$355

Mouse monoclonal [BAQ153A] antibody to CD11c for Flow Cytometry and ICC.

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-CD11c Antibody [BAQ153A]
Description
Mouse monoclonal [BAQ153A] antibody to CD11c.
Specificity
This antibody recognises bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection. Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC and flow cytometry.
Applications
Flow Cytometry, ICC
Dilutions
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Bovine, Goat, Sheep, Bison, Water Buffalo
Immunogen
Cells from multiple species.
Host
Mouse
Clonality
Monoclonal
Clone ID
BAQ153A
Isotype
IgM
Conjugate

Unconjugated

Purification
0.2µM sterile filtered.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide.
Storage
Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Mouse anti Bovine CD11c, clone BAQ153A, recognizes bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection (Sei et al. 2016). Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC (Palmer et al. 2011) and flow cytometry (Sei et al. 2016).
Synonyms
CD11 antigen-like family member C, Integrin alpha-X, ITGAX, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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