Recombinant Anti-c-Myc Antibody [MYC/7683R] (A314803)

Anti-c-Myc Antibody [MYC/7683R]

Recombinant rabbit monoclonal [MYC/7683R] antibody to c-Myc.

It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

HL-60 cells. Human cervical carcinoma or heart tissue.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human MYC protein. The exact sequence is proprietary.

Rabbit

Monoclonal

MYC/7683R

kappa

Protein A/G chromatography.

200 µg/ml

62-64 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

BHLHE39, Class E basic helix-loop-helix protein 39, MYC, Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64