Recombinant Anti-BRG1 Antibody [BRG1/7633R] - BSA and Azide free (A315911)

Anti-BRG1 Antibody [BRG1/7633R] - BSA and Azide free

Recombinant rabbit monoclonal [BRG1/7633R] antibody to BRG1.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/ SNF, including the NURF (nucleosome remodeling factor).

ELISA, WB, IHC-P

HeLa or HEK-293T cells. Ubiquitous nuclear expression.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 200-400) of human SMARCA4 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

BRG1/7633R

kappa

Protein A/G chromatography.

1 mg/ml

185 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ATP-dependent helicase SMARCA4, BAF190A, BRG1-associated factor 190A, Mitotic growth and transcription activator, Protein brahma homolog 1, Protein BRG-1, SMARCA4, SNF2B, SNF2L4, Transcription activator BRG1