Anti-beta Actin Antibody [4C2] (A279363)

Anti-beta Actin Antibody [4C2]

Mouse monoclonal [4C2] antibody to beta Actin.

This antibody recognises cytoplasmic actin beta (known also as ACTB and Beta Actin), a 41.7 kDa cytoskeletal protein.Actins are highly conserved proteins that are involved in cell motility, structure and integrity and are ubiquitously expressed in all eukaryotic cells. Six different isoforms of actin have been identified in mammals. Clone 4C2 is highly specific for cytoplasmic actin ß and does not react with other actin isoforms. Mouse anti Human actin beta, clone 4C2 has been used to look at the remodeling of the actin cytoskeleton following sendai virus infection and the specific role of the viral M protein in actin remodeling.

WB, IF, IHC-Fr

IHC-Fr: 1:50 - 1:100

Human, Rabbit, Pig, Mouse, Rat

Synthetic peptide corresponding to the acetylated N-terminal nonapeptide of beta-cytoplasmic actin, coupled to Keyhole Limpet Haemocyanin.

Mouse

Monoclonal

4C2

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human actin beta, clone 4C2, recognizes cytoplasmic actin beta (known also as ACTB and Beta Actin), a 41.7 kDa cytoskeletal protein.Actins are highly conserved proteins that are involved in cell motility, structure and integrity and are ubiquitously expressed in all eukaryotic cells. Six different isoforms of actin have been identified in mammals (Vandekerckhove et al. 1978). Clone 4C2 is highly specific for cytoplasmic actin ß and does not react with other actin isoforms. Mouse anti Human actin beta, clone 4C2 has been used to look at the remodeling of the actin cytoskeleton following sendai virus infection and the specific role of the viral M protein in actin remodeling (Miazza et al. 2011).

ACTB, Actin, cytoplasmic 1, Beta-actin