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Recombinant Anti-beta 2 Microglobulin Antibody [B2M/1857R] - BSA and Azide free (A252934)

Recombinant rabbit monoclonal [B2M/1857R] antibody to beta 2 Microglobulin for ELISA, Flow Cytometry and WB.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-beta 2 Microglobulin Antibody [B2M/1857R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [B2M/1857R] antibody to beta 2 Microglobulin.
Specificity
This antibody recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alphaheavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alphaheavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alphaheavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Applications
ELISA, Flow Cytometry, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human, Non-Human Primates
Immunogen
Recombinant full-length human B2M protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
B2M/1857R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
1 mg/ml
Molecular Weight
12 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-beta 2 Microglobulin Antibody [B2M/1857R] (A249754).
Synonyms
B2M, Beta-2-microglobulin
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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