Anti-Bcl6 Antibody [PCRP-BCL6-1B1] (A314488)

Overview
Specifications

Mouse monoclonal [PCRP-BCL6-1B1] antibody to Bcl6 for Flow Cytometry.

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Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 5-8 business days.

Specifications

Name

Anti-Bcl6 Antibody [PCRP-BCL6-1B1]

Description

Mouse monoclonal [PCRP-BCL6-1B1] antibody to Bcl6.

Specificity

Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Applications

Flow Cytometry

Positive Control

HeLa or MCF-7 cells.

Dilutions

Flow Cytometry: 1-2 µg/million cells

Reactivity

Human

Cross Reactivity

This antibody is predicted to cross react with Mouse and Rat.

Immunogen

Recombinant fragment (around Amino Acids 528-601) of human BCL6 protein.

Host

Mouse

Clonality

Monoclonal

Clone ID

PCRP-BCL6-1B1

Isotype

IgG2b

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Molecular Weight

95 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Synonyms

B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, BCL-5, BCL-6, BCL5, LAZ3, Protein LAZ-3, ZBTB27, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51, ZNF51

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

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