Recombinant mouse monoclonal [rDHTR/6818] antibody to Androgen Receptor.
Specificity
Androgen Receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones. The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues including prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors including osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 1-100, of human Androgen Receptor. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
rDHTR/6818
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
110 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate carcinoma tissue using Anti-Androgen Receptor Antibody [rDHTR/6818]. Inset: PBS instead of the primary antibody. Secondary antibody negative control.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate carcinoma tissue using Anti-Androgen Receptor Antibody [rDHTR/6818] at 2µg/ml.
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