Recombinant Anti-alpha Smooth Muscle Actin Antibody [ACTA2/1614R] (A278055)

Anti-alpha Smooth Muscle Actin Antibody [ACTA2/1614R]

Recombinant rabbit monoclonal [ACTA2/1614R] antibody to alpha Smooth Muscle Actin.

Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human ACTA2 protein.

Rabbit

Monoclonal

ACTA2/1614R

IgG

kappa

Protein A/G chromatography.

200 µg/ml

42 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-alpha Smooth Muscle Actin Antibody [ACTA2/1614R] - BSA and Azide free (A278643).

ACTA2, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein