Anti-alpha 1 Catenin Antibody [1G5] - BSA and Azide free (A251470)

Anti-alpha 1 Catenin Antibody [1G5] - BSA and Azide free

Mouse monoclonal [1G5] antibody to alpha 1 Catenin.

This antibody recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, -catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.'

Flow Cytometry, IF, WB

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml

Human

Human alpha Catenin fusion protein.

Mouse

Monoclonal

1G5

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

102 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-alpha 1 Catenin Antibody [1G5] (A248288).

Cadherin-associated protein, Catenin alpha-1, CTNNA1, Renal carcinoma antigen NY-REN-13