Anti-Adiponectin Antibody [ADPN/4256] - BSA and Azide free (A253797)

Anti-Adiponectin Antibody [ADPN/4256] - BSA and Azide free

Mouse monoclonal [ADPN/4256] antibody to Adiponectin.

This antibody reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Clone ADPN/4256 is used to detect plasma adiponectin concentrations. Clone ADPN/4256 is also used in a combination ELISA with clone ADPN/4255, acting as the capture antibody.

ELISA, IHC-P

IHC-P: 1-2 µg/ml

Human

Synthetic peptide corresponding to the tail region of the Adiponectin molecule.

Mouse

Monoclonal

ADPN/4256

IgG1

Protein A/G chromatography.

1 mg/ml

26-30 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Adiponectin Antibody [ADPN/4256] (A250617).

30 kDa adipocyte complement-related protein, ACDC, ACRP30, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, ADIPOQ, Adipose most abundant gene transcript 1 protein, apM-1, APM1, GBP28, Gelatin-binding protein