General Notes
Mouse anti Human Adiponectin antibody, clone Adn27 recognizes human adiponectin, also known as Acrp30, 30 kDa adipocyte complement-related protein, Adipocyte, C1q and collagen domain-containing protei or Gelatin-binding protein. Adiponectin is a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis. Mouse anti human adiponectin antibody, clone Adn27 has been successfully used as a capture reagent with mouse anti human adionectin antibody, Mouse anti Human adiponectin antibody, clone 5H7 (MCA2695) as a detection reagent in a sensitive Sandwich ELISA for the measurement of adiponectin in human plasma.