Anti-Carcinoembryonic Antigen Antibody [C66/1030] (Biotin) (A251123)

This product is discontinued

Anti-Carcinoembryonic Antigen Antibody [C66/1030] (Biotin) (A251123) has been discontinued and is no longer available.

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Name
Anti-Carcinoembryonic Antigen Antibody [C66/1030] (Biotin)
Description
Mouse monoclonal [C66/1030] antibody to Carcinoembryonic Antigen (Biotin).
Specificity
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, IHC-P: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human CEA protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
C66/1030
Isotype
IgG1
Light Chains
kappa
Conjugate

Biotin

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Carcinoembryonic antigen related cell adhesion molecule 5, Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, CEAM5_HUMAN, Meconium antigen 100
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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