Anti-Carcinoembryonic Antigen Antibody [C66/1030] (Biotin) (A251122)

Anti-Carcinoembryonic Antigen Antibody [C66/1030] (Biotin)

Mouse monoclonal [C66/1030] antibody to Carcinoembryonic Antigen (Biotin).

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human CEA protein.

Mouse

Monoclonal

IgG1

kappa

Biotin

Protein A/G chromatography.

1 mg/ml

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Carcinoembryonic antigen related cell adhesion molecule 5, Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, CEAM5_HUMAN, Meconium antigen 100

This product is for research use only. It is not intended for diagnostic or therapeutic use.