Anti-Caldesmon Antibody [h-CALD] - BSA and Azide free
Description
Mouse monoclonal [h-CALD] antibody to Caldesmon.
Specificity
This antibody recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (12080kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
SDS-PAGE analysis of Anti-Caldesmon Antibody [h-CALD] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
Figure 3: Western Blot - Anti-Caldesmon Antibody [h-CALD] - BSA and Azide free (A253560)
Western blot analysis of human ovary tissue lysate using Anti-Caldesmon Antibody [h-CALD].
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