Anti-Caldesmon Antibody [CALD1/820 + h-CALD] (A250383)

Anti-Caldesmon Antibody [CALD1/820 + h-CALD]

Mouse monoclonal [CALD1/820 + h-CALD] antibody to Caldesmon.

This antibody recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

IHC-P: 0.25-0.5 µg/ml

Human

Clone CALD1/820: Recombinant full-length human CALD1 protein. Clone h-CALD: Crude human uterus extract.

Mouse

Oligoclonal

CALD1/820 + h-CALD

IgG1, kappa + IgG1, kappa

Protein A/G chromatography.

200 µg/ml

150 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CAD, CALD 1, CALD1, CALD1_HUMAN, Caldesmon 1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, Caldesmon1, CDM, H CAD, HCAD, L CAD, LCAD, MGC21352, NAG22