Anti-C5a-R Antibody [S5/1] (PE) (A281720)

$515

Mouse monoclonal [S5/1] antibody to C5a-R (PE) for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-C5a-R Antibody [S5/1] (PE)
Description
Mouse monoclonal [S5/1] antibody to C5a-R (PE).
Specificity
This antibody recognises the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognise the heptameric peptide (D15DKDTLD21).Clone S5/1 has been shown to inhibit the binding of C5a to its receptor.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl
Reactivity
Human, Rabbit, Mustelid, Bovine, Ferret, Mink
Immunogen
C5aR - peptide: Met1 - Asn31.
Host
Mouse
Clonality
Monoclonal
Clone ID
S5/1
Isotype
IgG2a
Conjugate

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
Reconstitution dependent.
Product Form
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Storage
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light.
General Notes
Mouse anti Human CD88 antibody, clone S5/1 recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognise the heptameric peptide (D15DKDTLD21).Clone S5/1 has been shown to inhibit the binding of C5a to its receptor.
Synonyms
ANAPHYLATOXIN RECEPTOR, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin receptor, C5a ligand, C5aR, c5ar1, C5AR_HUMAN, C5R1, CD88, CD88 antigen, Complement component 5 receptor 1, Complement component 5 receptor 2, Complement component 5a receptor 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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