Anti-C3d Antibody [C3D/2891] (A250214)

Mouse monoclonal [C3D/2891] antibody to C3d for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-C3d Antibody [C3D/2891]
Description
Mouse monoclonal [C3D/2891] antibody to C3d.
Specificity
The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2). CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the natural antibody repertoire. This pH- and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity.
Applications
ELISA
Reactivity
Human
Immunogen
Recombinant full-length human Complement C3 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
C3D/2891
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
35 kDa (predicted)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-C3d Antibody [C3D/2891] - BSA and Azide free (A253394).
Synonyms
Acylation stimulating protein cleavage product, AHUS5, ARMD9, ASP, C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CO3_HUMAN, Complement C3, Complement C3c alpha' chain fragment 2, Complement C3d fragment, Complement component 3, Complement component C3, CPAMD1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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