Recombinant Anti-beta III Spectrin Antibody [SPTBN2/2887R] (A250048)

Anti-beta III Spectrin Antibody [SPTBN2/2887R]

Recombinant rabbit monoclonal [SPTBN2/2887R] antibody to beta III Spectrin .

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

Flow Cytometry, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 356-475, of human SPTBN2 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

SPTBN2/2887R

IgG

Protein A/G chromatography.

200 µg/ml

246 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-beta III Spectrin Antibody [SPTBN2/2887R] - BSA and Azide free (A253228).