Anti-beta III Spectrin Antibody [RG/26] (A250042)

Mouse monoclonal [RG/26] antibody to beta III Spectrin for ELISA, WB, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-beta III Spectrin Antibody [RG/26]
Description
Mouse monoclonal [RG/26] antibody to beta III Spectrin .
Specificity
Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
Applications
ELISA, WB, IF, IHC-P
Dilutions
WB: 1-2 µg/ml, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human, Mouse, Rat
Immunogen
Red cell membranes.
Host
Mouse
Clonality
Monoclonal
Clone ID
RG/26
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
246 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-beta III Spectrin Antibody [RG/26] - BSA and Azide free (A253222).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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