Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310)

Name: Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free
Brand: Antibodies.com
SKU: A323310
Price: 295.0 USD
Availability: InStock

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$295

Recombinant human monoclonal antibody to FGFR2 for ELISA, FACS, Functional Assay and In Vivo.

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Delivery

Freight Charges

$40 to United States

Lead Time

7-10 Business Days

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Telephone

+1 (314) 370-6046

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Recombinant Antibody

Specifications

Name

Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free

Description

Recombinant human monoclonal antibody to FGFR2.

Applications

ELISA, FACS, Functional Assay, In Vivo

Reactivity

Human, Mouse, Cynomolgus Macaque

Host

Human

Clonality

Monoclonal

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A affinity chromatography.

Concentration

Reconstitution dependent.

Molecular Weight

This antibody has a predicted MW of 144 kDa.

Purity

> 95% (by SDS-PAGE and SEC-HPLC).

Product Form

Lyophilized

Reconstitution

Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!

Formulation

Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyms

bacteria-expressed kinase, BBDS, BEK, BEK fibroblast growth factor receptor, BFR1, CD332, CD332 antigen, CEK3, CFD1, Craniofacial dysostosis 1, ECT1, FGF receptor, FGFR 2, FGFR-2, FGFR2_HUMAN, Fibroblast growth factor receptor 2, Hydroxyaryl protein kinase, Jackson Weiss syndrome, JWS, K SAM, K-sam, Keratinocyte growth factor receptor, Keratinocyte growth factor receptor 2, KGFR, KSAM, protein tyrosine kinase, receptor like 14, soluble FGFR4 variant 4, TK14, TK25

Suitable Secondaries

See all Anti-Human IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (6)

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Figure 1: SDS-PAGE - Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310)

SDS-PAGE analysis of Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.

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Figure 2: Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310)

SEC-HPLC analysis of Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310) confirms that the purity of this antibody is 100%.

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Figure 3: Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310)

SNU-16 cells were stained with Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC₅₀ = 0.5368 µg/ml.

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Figure 4: Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310)

Bemarituzumab Biosimilar - Anti-FGFR2 Antibody - Low endotoxin, Azide free (A323310) induced ADCC activity was evaluated using human FGFR2 HEK293 Reporter Cell. The max induction fold was approximately 25.

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