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Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)

SDS-PAGE - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.com SEC-HPLC - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.com ELISA - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.com Research in vivo - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.com
Recombinant Antibody
$295
Product Datasheet

Recombinant human monoclonal antibody to PD-L1 for ELISA, FACS, Functional Assay and In Vivo.

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Freight Charges
$40 to United States
Lead Time
7-10 Business Days

Telephone
+1 (314) 370-6046
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Email
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Name
Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free
Description
Recombinant human monoclonal antibody to PD-L1.
Applications
ELISA, FACS, Functional Assay, In Vivo
Reactivity
Human, Mouse, Cynomolgus Macaque, Dog, Rat, Rabbit
Host
Human
Clonality
Monoclonal
Isotype
IgG1
Light Chains
lambda
Conjugate

Unconjugated

Purification
Protein A affinity chromatography.
Concentration
Reconstitution dependent.
Molecular Weight
This antibody has a predicted MW of 150 kDa.
Purity
> 95% (by SDS-PAGE and SEC-HPLC).
Product Form
Lyophilized
Reconstitution
Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!
Formulation
Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Synonyms
B7 H, B7 H1, B7 homolog 1, B7-H1, B7H, B7H1, CD 274, CD274, CD274 antigen, CD274 molecule, MGC142294, MGC142296, OTTHUMP00000021029, PD L1, PD1L1_HUMAN, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL 1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, RGD1566211
Suitable Secondaries
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
SDS-PAGE - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.comEnlarge Image
Figure 1: SDS-PAGE - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)
SDS-PAGE analysis of Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.
SEC-HPLC - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.comEnlarge Image
Figure 2: Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)
SEC-HPLC analysis of Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) confirms that the purity of this antibody is 98.22%.
ELISA - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.comEnlarge Image
Figure 3: Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)
Immobilized recombinant human PD-L1 protein (Fc tag) at 2 µg/ml is bound by Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294). EC50 = 0.03725 µg/ml.
Research in vivo - Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) - Antibodies.comEnlarge Image
Figure 4: Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)
Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294) inhibited the tumor growth of MC38 on hLAG3 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 32.6% at 1 mpk at D28.
Publishing research using Avelumab Biosimilar - Anti-PD-L1 Antibody - Low endotoxin, Azide free (A323294)? Please let us know so that we can list the citation on this page.

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