Anti-ATG7 Antibody (A283171)

Anti-ATG7 Antibody

Rabbit polyclonal antibody to ATG7.

This antibody recognises human Autophagy-related protein 7, known also as Ubitiquin Activating Enzyme-E1 like Protein, ATG7, and APG7. ATG7 is a ~78 kDa cytoplasmic protein.In mammalian cells, ATG7 is essential for autophagy conjugation systems, autophagosome formation, and starvation-induced bulk degradation of proteins and organelles. Caspase-8 may alter ATG7 levels and thus the ATG7 program of autophagic cell death. ATG7 is evolutionarily conserved exhibiting high homology within mammalian species. It expressed in wide range of tissues including kidney, liver, bone marrow and lymph nodes.

WB, IHC-Fr

IHC-Fr: 10 µg/ml, WB: 1 - 2 µg/ml

Human, Mouse

A peptide corresponding to 17 amino acids near the C-terminus of human ATG7.

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human ATG7 (C-Terminal) antibody recognizes human Autophagy-related protein 7, known also as Ubitiquin Activating Enzyme-E1 like Protein, ATG7, and APG7. ATG7 is a ~78 kDa cytoplasmic protein.In mammalian cells, ATG7 is essential for autophagy conjugation systems, autophagosome formation, and starvation-induced bulk degradation of proteins and organelles. Caspase-8 may alter ATG7 levels and thus the ATG7 program of autophagic cell death (Yu et al. 2004).ATG7 is evolutionarily conserved exhibiting high homology within mammalian species. It expressed in wide range of tissues including kidney, liver, bone marrow and lymph nodes.

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