Anti-ARID1A Antibody [ARID1A/7735] (A314480)

Anti-ARID1A Antibody [ARID1A/7735]

Mouse monoclonal [ARID1A/7735] antibody to ARID1A.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.

Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1900-2000) of human ARID1A protein. The exact sequence is proprietary.

Mouse

Monoclonal

ARID1A/7735

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

165-320 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

actin-dependent regulator of chromatin subfamily F member 1, ARI1A_HUMAN, ARID domain containing protein 1A, ARID domain-containing protein 1A, AT rich interactive domain 1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain containing protein 1A, AT-rich interactive domain-containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1 associated factor 250, BRG1 associated factor 250a, BRG1-associated factor 250, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, Osa homolog 1, OSA1, OSA1 nuclear protein, P270, SMARCF1, SWI like protein, SWI SNF complex protein p270, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, SWI/SNF-related