Recombinant rabbit monoclonal [ARG1/6790R] antibody to Arginase 1.
Specificity
This antibody recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Applications
WB, IHC
Dilutions
WB: 2-4 µg/ml, IHC-P: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 300-400, of human Arginase 1. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ARG1/6790R
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
35-38 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
A I, Al, ARG 1, arg1, ARGI1_HUMAN, Arginase liver, Arginase type I, Arginase, liver, Arginase-1, Arginase1, Liver Arginase, Liver type arginase, Liver-type arginase, Type I arginase
Figure 1: Western Blot - Anti-Arginase 1 Antibody [ARG1/6790R] (A278012)
Western blot analysis of human liver tissue lysate using Anti-Arginase 1 Antibody [ARG1/6790R].
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