Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850)

Name: Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free
Brand: Antibodies.com
SKU: A318850
Price: 275.0 USD
Availability: InStock

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$275

Recombinant human monoclonal antibody to Interferon alpha/beta Receptor 1 for ELISA and Flow Cytometry.

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Freight Charges

$40 to United States

Lead Time

7-8 Business Days

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Recombinant Antibody

Specifications

Name

Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free

Description

Recombinant human monoclonal antibody to Interferon alpha/beta Receptor 1.

Applications

ELISA, Flow Cytometry

Dilutions

ELISA: 1:5,000-10,000, Flow Cytometry: 1:100

Reactivity

Human

Host

Human

Clonality

Monoclonal

Isotype

IgG1

Conjugate

Unconjugated

Purification

Affinity chromatography.

Concentration

Reconstitution dependent.

Product Form

Lyophilized

Reconstitution

Reconstitute with distilled sterile water.

Formulation

Lyophilized from sterile Phosphate Buffered Saline, pH 7.4. Normally 5%–8% Trehalose is added as a protectant before lyophilization.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

General Notes

Prior to reconstitution, centrifuge the vial at 5,000g for 3-5 minutes at room temperature. Reconstitute with appropriate volume of distilled sterile water to bring product to 1mg/ml concentration. After addition of distilled sterile water, mix by gentle tapping. Note: It is not recommended to vortex or vigorously pipette the sample.

Synonyms

Alpha type antiviral protein, Antiviral protein, alpha-type, Antiviral protein, beta-type, AVP, Beta type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, IFN alpha REC, IFN alpha receptor, IFN alpha/beta Receptor alpha, IFN beta receptor, IFN Interferon-beta receptor, IFN-alpha/beta receptor 1, IFN-R-1, IFNAR, IFNAR1, IFNBR, IFRC, INAR1_HUMAN, Interferon (alpha beta and omega) receptor 1, interferon alpha and beta receptor subunit 1, Interferon alpha/beta receptor alpha chain, Interferon beta receptor 1, interferon receptor 1, Interferon-alpha receptor, Type I interferon receptor 1

Suitable Secondaries

See all Anti-Human IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (4)

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Figure 1: Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850)

ELISA plates were pre-coated with Recombinant Human Interferon alpha/beta Receptor 1 Protein (6×His Tag) (A317909) at 1 µg/ml (100 µl/well) which can bind Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850) in a linear range of 0.61-39.06 ng/ml.

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Figure 2: Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850)

ELISA plates were pre-coated with Recombinant Human Interferon alpha/beta Receptor 1 Protein (Fc Tag) (A318001) at 2 µg/ml (100 µl/well) which can bind Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850) in a linear range of 0.73-187.50 ng/ml. In order to specifically detect Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850), Mouse Anti-Human Fab Antibody was used as detection antibody.

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Figure 3: Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850)

ELISA plates were pre-coated with Recombinant Human Interferon alpha/beta Receptor 1 Protein (Fc Tag) (A318032) at 2 µg/ml (100 µl/well) which can bind Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850) in a linear range of 1.22-312.50 ng/ml.

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Figure 4: Flow Cytometry - Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850)

Flow cytometry analysis of 1µg/ml of Anifrolumab Biosimilar - Anti-Interferon alpha/beta Receptor 1 Antibody - BSA and Azide free (A318850) on Expi293 cells transfected with Human IFNAR1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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