Anti-AMH Antibody [AMH/7354] (A314475)

$765

Mouse monoclonal [AMH/7354] antibody to AMH for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-AMH Antibody [AMH/7354]
Description
Mouse monoclonal [AMH/7354] antibody to AMH.
Specificity
The transforming growth factor superfamily are involved in embryonic development and adult tissue homeostasis. The MIS glycoprotein is produced by the Sertoli cells of the testes. Fetal testes produce both MIS and testosterone, the presence of which result in male offspring. Absence of MIS and testosterone in a developing fetus results in the induction of Mullerian duct differentiation, and Wolffian duct development is not induced. Testosterone induces the differentiation of the Wolffian ducts whereas MIS causes regression of the Muellerian duct. MIS inhibits the growth of tumors derived from tissues of Mullerian duct origin. MIS can also inhibit the autophosphorylation of the EGF receptor in vitro. Defects in anti-Muellerian hormone are the cause of persistent Muellerian duct syndrome type I (PMDS-1). PMDS-1 is a form of male pseudo hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
Applications
IHC-P
Positive Control
Human or mouse ovary tissue.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment of the C-terminus of human AMH (aa 460-560). The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
AMH/7354
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
70 kDa (reduced) / 140 kDa (nonreduced)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Anti muellerian hormone, MIF, MIS, Muellerian inhibiting factor, Mullerian inhibiting substance
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-AMH Antibody [AMH/7354] (A314475)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-AMH Antibody [AMH/7354] (A314475)

Top