Anti-alpha 1 Fetoprotein Antibody [2I9/2 (166)] (A279245)

Anti-alpha 1 Fetoprotein Antibody [2I9/2 (166)]

Mouse monoclonal [2I9/2 (166)] antibody to alpha 1 Fetoprotein.

This antibody recognises alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a ~68 kDa plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adultsElevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome. Mouse anti Human alpha fetoprotein antibody, clone 219/2 does not cross-react with human albumin and other human serum proteins.

Human

Human fetal cord serum.

Mouse

Monoclonal

2I9/2 (166)

IgG

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human alpha fetoprotein antibody, clone 219/2 recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a ~68 kDa plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adultsElevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome.Mouse anti Human alpha fetoprotein antibody, clone 219/2 does not cross-react with human albumin and other human serum proteins.

Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein, HPAFP