Mouse monoclonal [AAT/4615] antibody to alpha 1 Antitrypsin.
Specificity
It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Applications
IHC-P
Positive Control
Human tonsil, hepatocellular carcinoma or histiocytoma (IHC).
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 200-400) of human SERPINA1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
AAT/4615
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
46 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
![SDS-PAGE - Anti-alpha 1 Antitrypsin Antibody [AAT/3167R] - BSA and Azide free (A252814) - Antibodies.com](https://cdn.antibodies.com/image/catalog/252/A252814_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-alpha 1 Antitrypsin Antibody [AAT/3167R] (A249634) - Antibodies.com](https://cdn.antibodies.com/image/catalog/249/A249634_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-alpha 1 Antitrypsin Antibody [AAT/1378] (A249631) - Antibodies.com](https://cdn.antibodies.com/image/catalog/249/A249632_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-alpha 1 Antitrypsin Antibody [AAT/1378] - BSA and Azide free (A252811) - Antibodies.com](https://cdn.antibodies.com/image/catalog/252/A252812_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-alpha 1 Antitrypsin Antibody [AAT/1379] (A249632) - Antibodies.com](https://cdn.antibodies.com/image/catalog/249/A249633_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-alpha 1 Antitrypsin Antibody [AAT/1379] - BSA and Azide free (A252812) - Antibodies.com](https://cdn.antibodies.com/image/catalog/252/A252813_1.jpg?profile=product_alternative)
![Western Blot - Anti-alpha 1 Antitrypsin Antibody [ARC1212] (A307644) - Antibodies.com](https://cdn.antibodies.com/image/catalog/307/A307644_1.jpg?profile=product_alternative)