Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [ALPL/597] (A248636)

Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [ALPL/597]

Mouse monoclonal [ALPL/597] antibody to Alkaline Phosphatase, Tissue Non-Specific.

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.

IHC-P: 1-2 µg/ml

Human, Bovine

Recombinant human ALPL protein.

Mouse

Monoclonal

ALPL/597

IgG1

kappa

Unconjugated

200 µg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [ALPL/597] - BSA and Azide free (A251818).

AKP2, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, Alkaline phosphatase, tissue-nonspecific isozyme, Alkaline phosphomonoesterase, Alpl, AP TNAP, AP-TNAP, APTNAP, BAP, FLJ40094, FLJ93059, Glycerophosphatase, HOPS, Liver/bone/kidney type alkaline phosphatase, MGC161443, MGC167935, PHOA, PPBT_HUMAN, Tissue non specific alkaline phosphatase, Tissue nonspecific ALP, TNAP, TNSALP