Recombinant Anti-Aldose reductase Antibody [rAKR1B1/7296] (A314444)

$765

Recombinant mouse monoclonal [rAKR1B1/7296] antibody to Aldose reductase for IF, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Aldose reductase Antibody [rAKR1B1/7296]
Description
Recombinant mouse monoclonal [rAKR1B1/7296] antibody to Aldose reductase.
Specificity
AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Applications
IF, WB, IHC-P
Positive Control
MOLT4, Jurkat or Raji cells. Human kidney or colon carcinoma.
Dilutions
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human full-length AKR1B1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
rAKR1B1/7296
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
37 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
ADR, AKR1B 1, AKR1B1, Aldehyde reductase, Aldehyde reductase 1, Aldo keto reductase family 1, member B1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), aldr 1, aldr1, ALDR_HUMAN, ALR2, AR, Lii5 2 CTCL tumor antigen, Low Km aldose reductase, MGC1804
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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