Recombinant Anti-Aldose reductase Antibody [rAKR1B1/7296] (A314444)

Anti-Aldose reductase Antibody [rAKR1B1/7296]

Recombinant mouse monoclonal [rAKR1B1/7296] antibody to Aldose reductase.

AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.

IF, WB, IHC-P

MOLT4, Jurkat or Raji cells. Human kidney or colon carcinoma.

IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant human full-length AKR1B1 protein.

Mouse

Monoclonal

rAKR1B1/7296

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

37 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ADR, AKR1B 1, AKR1B1, Aldehyde reductase, Aldehyde reductase 1, Aldo keto reductase family 1, member B1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), aldr 1, aldr1, ALDR_HUMAN, ALR2, AR, Lii5 2 CTCL tumor antigen, Low Km aldose reductase, MGC1804