Recombinant Anti-AKT1 Antibody [AKT1/3898R] (A248470)

Anti-AKT1 Antibody [AKT1/3898R]

Recombinant rabbit monoclonal [AKT1/3898R] antibody to AKT1.

This antibody recognizes a protein of 62kDa, which is identified as AKT1The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.

WB, ELISA

WB: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 85-189, of human AKT1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

AKT1/3898R

IgG

Protein A/G chromatography.

200 µg/ml

62 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AKT1 Antibody [AKT1/3898R] - BSA and Azide free (A251652).

AKT, AKT 1, AKT1_HUMAN, MGC99656, PKB, PKB-ALPHA, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, RAC Alpha, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha