Anti-Adenovirus Antibody [B025 (AD51)] (A279729)

Anti-Adenovirus Antibody [B025 (AD51)]

Mouse monoclonal [B025 (AD51)] antibody to Adenovirus.

This antibody recognises all human adenoviruses serotypes. The most common infections caused by adenovirus are respiratory tract infections but some infections may also lead to conjunctivitis, skin-rash, diarrhea and bladder infections. Infant and children are most commonly affected by adenoviruses. Adenoviruses are icosahedral non-enveloped linear double-stranded DNA viruses. There are at least 51 serotypes, which are categorized into 6 species (A-F) based on molecular criteria. The virus capsid is composed of three different proteins: 12 fiber attachment proteins associated with 12 penton base proteins and 240 hexon proteins, which form the main capsid component. Mouse anti adenovirus antibody, clone B025 (AD51) reacts with the adenovirus specific hexon polypeptide. Due to their infectivity to both quiescent and proliferating cells, adenoviruses have also been used as vectors in vaccination and in gene therapy (Thomas et al. 2002 and Abad et al. 2002).

IHC-P, ELISA, IHC-Fr

Viral

Adenovirus type 3.

Mouse

Monoclonal

B025 (AD51)

IgG2a

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

>90% (by SDS-PAGE).

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti adenovirus antibody, clone B025 (AD51) recognizes all human adenoviruses serotypes. The most common infections caused by adenovirus are respiratory tract infections but some infections may also lead to conjunctivitis, skin-rash, diarrhea and bladder infections. Infant and children are most commonly affected by adenoviruses. Adenoviruses are icosahedral non-enveloped linear double-stranded DNA viruses. There are at least 51 serotypes, which are categorized into 6 species (A-F) based on molecular criteria. The virus capsid is composed of three different proteins: 12 fiber attachment proteins associated with 12 penton base proteins and 240 hexon proteins, which form the main capsid component (Ebner et al. 2005). Mouse anti adenovirus antibody, clone B025 (AD51) reacts with the adenovirus specific hexon polypeptide. Due to their infectivity to both quiescent and proliferating cells, adenoviruses have also been used as vectors in vaccination and in gene therapy (Thomas et al. 2002 and Abad et al. 2002).