Anti-TLR9 Antibody (A283239)

Anti-TLR9 Antibody

Goat polyclonal antibody to TLR9.

This antibody recognises an epitope within the N-terminal region of CD289, otherwise known as Toll-like receptor 9 (TLR9), a type I transmembrane glycoprotein and member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity. Goat anti Human CD289 antibody is suitable for use in immunocytochemistry on acetone fixed cells.

WB, IHC-P

IHC-P 1: 1:250, WB: 1:1,000

Human, Mouse

Synthetic peptide sequence SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL corresponding to amino acids 205-235 within the N-terminal domain of human CD289.

SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL

Goat

IgG

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

CD289, Toll-like receptor 9